Machine learning-based diagnostic model of lymphatics-associated genes for new therapeutic target analysis in intervertebral disc degeneration

Machine learning-based diagnostic model of lymphatics-associated genes for new therapeutic target analysis in intervertebral disc degeneration

BackgroundLow back pain resulting from intervertebral disc degeneration (IVDD) represents a significant global social problem. There are notable differences in the distribution of lymphatic vessels (LV) in normal and pathological intervertebral discs. Nevertheless, the molecular mechanisms of lympha...

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Bibliographic Details
Main Authors: Maoqiang Lin, Shaolong Li, Yabin Wang, Guan Zheng, Fukang Hu, Qiang Zhang, Pengjie Song, Haiyu Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
intervertebral disc degeneration
machine learning
diagnostic model
lymphatic-associated gene
therapeutic target
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1441028/full
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