A simulation study to quantitatively assess the performance of electronic prescribing systems in English NHS Hospital Trusts

Abstract Prescribing errors are a source of preventable harm in healthcare, which may be mitigated using Electronic Prescribing (EP) systems. Anyone who routinely prescribes medication could benefit from digitally assisted automated checks to identify whether a prescription should potentially not be...

Full description

Saved in:
Bibliographic Details
Main Authors: Stephanie Klein, Athanasios Tsanas, Jamie Coleman, Rebecca Osselton, Jude Heed, Ann Slee, Neil Watson
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-86112-w
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832594802059771904
author Stephanie Klein
Athanasios Tsanas
Jamie Coleman
Rebecca Osselton
Jude Heed
Ann Slee
Neil Watson
author_facet Stephanie Klein
Athanasios Tsanas
Jamie Coleman
Rebecca Osselton
Jude Heed
Ann Slee
Neil Watson
author_sort Stephanie Klein
collection DOAJ
description Abstract Prescribing errors are a source of preventable harm in healthcare, which may be mitigated using Electronic Prescribing (EP) systems. Anyone who routinely prescribes medication could benefit from digitally assisted automated checks to identify whether a prescription should potentially not be allowed (e.g. drug allergy). National Health Service (NHS) Trusts have implemented a range of EP systems; however, their performance has not hitherto been evaluated. We developed the web-based Electronic Prescribing Risk and Safety Evaluation (ePRaSE) tool, which comprises a bank of prescribing scenarios to evaluate the performance of EP systems. We solicited ePRaSE testing: 68 pharmacists from across 45 English NHS Trusts, utilising 13 different EP systems volunteered for the study. We found considerable variability in mitigation performance (systems correctly identifying risk of error when prescribing) across both NHS Trusts and EP systems. Moreover, we found that mitigation performance varied considerably across NHS Trusts using the same EP system, strongly suggesting there are opportunities to optimise performance within systems. The ePRaSE tool is effective in identifying variability in risk management between NHS Trusts and EP systems. Wider use of this tool may facilitate improvements in EP system configurations, thus minimising potential harm from prescribing errors.
format Article
id doaj-art-f6ffb8ed2d5542f094a1fcc6601ac4b0
institution Kabale University
issn 2045-2322
language English
publishDate 2025-01-01
publisher Nature Portfolio
record_format Article
series Scientific Reports
spelling doaj-art-f6ffb8ed2d5542f094a1fcc6601ac4b02025-01-19T12:20:11ZengNature PortfolioScientific Reports2045-23222025-01-0115111310.1038/s41598-025-86112-wA simulation study to quantitatively assess the performance of electronic prescribing systems in English NHS Hospital TrustsStephanie Klein0Athanasios Tsanas1Jamie Coleman2Rebecca Osselton3Jude Heed4Ann Slee5Neil Watson6Pharmacy Department, Newcastle Upon Tyne Hospitals NHS Foundation TrustUsher Institute, University of EdinburghInstitute of Clinical Sciences, University of Birmingham Medical SchoolResearch Software Engineering, University of Newcastle upon TyneSchool of Pharmacy, Faculty of Medical Sciences, Newcastle UniversityUsher Institute, University of EdinburghPharmacy Department, Newcastle Upon Tyne Hospitals NHS Foundation TrustAbstract Prescribing errors are a source of preventable harm in healthcare, which may be mitigated using Electronic Prescribing (EP) systems. Anyone who routinely prescribes medication could benefit from digitally assisted automated checks to identify whether a prescription should potentially not be allowed (e.g. drug allergy). National Health Service (NHS) Trusts have implemented a range of EP systems; however, their performance has not hitherto been evaluated. We developed the web-based Electronic Prescribing Risk and Safety Evaluation (ePRaSE) tool, which comprises a bank of prescribing scenarios to evaluate the performance of EP systems. We solicited ePRaSE testing: 68 pharmacists from across 45 English NHS Trusts, utilising 13 different EP systems volunteered for the study. We found considerable variability in mitigation performance (systems correctly identifying risk of error when prescribing) across both NHS Trusts and EP systems. Moreover, we found that mitigation performance varied considerably across NHS Trusts using the same EP system, strongly suggesting there are opportunities to optimise performance within systems. The ePRaSE tool is effective in identifying variability in risk management between NHS Trusts and EP systems. Wider use of this tool may facilitate improvements in EP system configurations, thus minimising potential harm from prescribing errors.https://doi.org/10.1038/s41598-025-86112-wClinical pharmacy information systemsDecision support systemsClinicalInformaticsMedical order entry systemsSafety management
spellingShingle Stephanie Klein
Athanasios Tsanas
Jamie Coleman
Rebecca Osselton
Jude Heed
Ann Slee
Neil Watson
A simulation study to quantitatively assess the performance of electronic prescribing systems in English NHS Hospital Trusts
Scientific Reports
Clinical pharmacy information systems
Decision support systems
Clinical
Informatics
Medical order entry systems
Safety management
title A simulation study to quantitatively assess the performance of electronic prescribing systems in English NHS Hospital Trusts
title_full A simulation study to quantitatively assess the performance of electronic prescribing systems in English NHS Hospital Trusts
title_fullStr A simulation study to quantitatively assess the performance of electronic prescribing systems in English NHS Hospital Trusts
title_full_unstemmed A simulation study to quantitatively assess the performance of electronic prescribing systems in English NHS Hospital Trusts
title_short A simulation study to quantitatively assess the performance of electronic prescribing systems in English NHS Hospital Trusts
title_sort simulation study to quantitatively assess the performance of electronic prescribing systems in english nhs hospital trusts
topic Clinical pharmacy information systems
Decision support systems
Clinical
Informatics
Medical order entry systems
Safety management
url https://doi.org/10.1038/s41598-025-86112-w
work_keys_str_mv AT stephanieklein asimulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT athanasiostsanas asimulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT jamiecoleman asimulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT rebeccaosselton asimulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT judeheed asimulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT annslee asimulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT neilwatson asimulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT stephanieklein simulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT athanasiostsanas simulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT jamiecoleman simulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT rebeccaosselton simulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT judeheed simulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT annslee simulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts
AT neilwatson simulationstudytoquantitativelyassesstheperformanceofelectronicprescribingsystemsinenglishnhshospitaltrusts