Oxypalmatine promotes apoptosis and protective autophagy in lung cancer cells via the PI3K/AKT pathway
Abstract Oxypalmatine (OPT), a small molecule alkaloid isolated from Phellodendron amurense, is a bioactive compound with promising anticancer potential. We evaluated the efficacy of OPT using four lung adenocarcinoma cell lines and four patient-derived organoid tissues. Additionally, the anticancer...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | Cancer Cell International |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12935-025-03939-z |
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