Subtherapeutic lithium supplementation causes physiological eccentric cardiac hypertrophy in young‐adult wild‐type male mice

Abstract Six weeks of low‐dose lithium (Li) supplementation has been shown to improve the activity of cardiac sarco(endo)plasmic reticulum calcium (Ca2+)‐ATPase (SERCA) in C57BL/6J wild‐type (WT) male mice. Improvements in myocardial SERCA function can lead to improvements in systolic and diastolic...

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Bibliographic Details
Main Authors: Sophie I. Hamstra, Mia S. Geromella, Peter Tiidus, Panagiota Klentrou, Rebecca E. K. MacPherson, Val A. Fajardo
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Physiological Reports
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Online Access:https://doi.org/10.14814/phy2.70299
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