Changes in expression of NLRP3 inflamasome and IL-1β in the development of oxazolone-induced colitis in rats and on the background of administration of simvastatin and interleukin-1β receptor antagonist

Changes in expression of NLRP3 inflamasome and IL-1β in the development of oxazolone-induced colitis in rats and on the background of administration of simvastatin and interleukin-1β receptor antagonist

The aim. To study the expression of mRNA of the NLRP3 inflammasome and proinflammatory cytokine IL-1β in the inflamed colon of rats with experimental oxazolone-induced colitis and against the background of the introduction of simvastatin and antagonist of interleukin-1 receptors. Materials and me...

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Bibliographic Details
Main Authors: O. S. Zherebiatiev, N. M. Polishchuk
Format: Article
Language:English
Published: Zaporizhzhia State Medical and Pharmaceutical University 2021-05-01
Series:Patologìâ
Subjects:
colitis
nlrp3 protein
inflammasomes
il-1β
Online Access:http://pat.zsmu.edu.ua/article/view/228928/230673
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