Unveiling the influence of caffeine on topiramate: metabolomic marker analysis using liquid chromatography-mass spectrometry

BackgroundEpilepsy affects approximately 70 million individuals globally, posing significant neurobiological and psychological challenges. Despite the availability of numerous antiepileptic treatments, one-third of patients remain resistant to therapy, with a limited understanding of caffeine (CAF)...

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Bibliographic Details
Main Authors: Adrian Bartoszek, Ewa Paszkowska, Anna Kozub-Pędrak, Agata Sumara, Emilia Fornal
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1549993/full
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