Lactoferrin influences atherosclerotic progression by modulating macrophagic AMPK/mTOR signaling-dependent autophagy

Lactoferrin influences atherosclerotic progression by modulating macrophagic AMPK/mTOR signaling-dependent autophagy

Abstract This study aimed to explore the role of lactoferrin (LTF) in atherosclerosis (AS) and its possible mechanisms. Human left coronary artery tissues were collected and divided into control (CON), coronary heart disease (CHD) and sudden coronary death (SCD) groups. Pathologic changes (including...

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Bibliographic Details
Main Authors: Bing Xia, Jingwei Liang, Yanlin Lu, Jiuyang Ding, Jin Peng, Fangqin Li, Jialin Dai, Yubo Liu, Jie Wang, Changwu Wan, Peng Luo
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Lactoferrin
Atherosclerosis
Sudden coronary death
Autophagy
AMPK
mTOR
Online Access:https://doi.org/10.1038/s41598-025-95181-w
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https://doi.org/10.1038/s41598-025-95181-w

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