Ex vivo C5b-9 Deposition Test to Monitor Complement Activity in Clinical and Subclinical Atypical Hemolytic Uremic Syndrome and in Transplantation-Associated Thrombotic Microangiopathy

Ex vivo C5b-9 Deposition Test to Monitor Complement Activity in Clinical and Subclinical Atypical Hemolytic Uremic Syndrome and in Transplantation-Associated Thrombotic Microangiopathy

Introduction: Atypical hemolytic uremic syndrome (aHUS) is a complement system (CS)–mediated ultrarare disease that manifests as thrombotic microangiopathy (TMA) with preferential small kidney vessels involvement. Transient CS activation is also observed in secondary TMA or in patients at risk of de...

Full description

Saved in:
Bibliographic Details
Main Authors: Maria Martin, Carmen Llorens-Cebria, Juan León-Román, Janire Perurena-Prieto, Víctor Perez-Beltran, Silvia Saumell, Irina B. Torres, Irene Agraz, Joana Sellarès, Natàlia Ramos, Oriol Bestard, Mercedes López, Francesc Moreso, Gema Ariceta, Maria José Soler, Manuel Hernandez-Gonzalez, Conxita Jacobs-Cachá
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Kidney International Reports
Subjects:
aHUS
biomarkers
C5 blockade
C5b-9 deposition test
complement system
transplant-associated TMA
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024924016450
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2468024924016450

Similar Items