SIRT5-mediated PRKAA2 succinylation ameliorates apoptosis of human placental trophoblasts in hypertensive disorder complicating pregnancy

SIRT5-mediated PRKAA2 succinylation ameliorates apoptosis of human placental trophoblasts in hypertensive disorder complicating pregnancy

Purpose Hypertensive disorder complicating pregnancy (HDCP) is a serious clinical disorder syndrome during pregnancy. This study aims at finding novel targets for HDCP therapy.Methods HDCP-related mRNAs were firstly screened out and subjected to gene enrichment analysis. We chose protein kinase AMP-...

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Bibliographic Details
Main Authors: Feifei Ren, Mo Yang, Guangman Liu, Yuyan Qi, Aijie Li, Jia Li, Lili Zheng
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Clinical and Experimental Hypertension
Subjects:
PRKAA2
succinylation
SIRT5
HDCP
apoptosis
Online Access:https://www.tandfonline.com/doi/10.1080/10641963.2024.2358030
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https://www.tandfonline.com/doi/10.1080/10641963.2024.2358030

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