Impacts of chronic intermittent ethanol vapor and predator odor on ethanol intake and striatal D1 and CB1 cannabinoid receptor-expressing medium spiny neurons

Impacts of chronic intermittent ethanol vapor and predator odor on ethanol intake and striatal D1 and CB1 cannabinoid receptor-expressing medium spiny neurons

IntroductionStress is a risk factor for ethanol use disorders, which has been modeled by chronic intermittent ethanol (CIE) vapor exposure. Repeated stress alters CB1 receptor signaling, which could influence ethanol-related behaviors. Striatal CB1 receptors regulate D1-medium spiny neurons (D1-MSNs...

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Main Authors:	Cristiane Aparecida Favoretto, Allyson Nguyen, Gabriela R. Chacon, Amanda J. Roberts, Tali Nadav, Saumya Ranjan, Luisa Becker Bertotto, Fábio Cardoso Cruz, Eric P. Zorrilla
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Neuroscience
Subjects:	alcohol stress D1-medium spiny neurons CB1 cannabinoid receptors Fos corticosterone
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2025.1568952/full
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