Primary Ovarian Choriocarcinoma: Rare Entity
Background. Primary pure ovarian choriocarcinoma is a rare aggressive tumor which can be nongestational arising from germ cells or gestational origin. Preoperative diagnosis of extrauterine choriocarcinoma is challenging due to nonspecific clinical presentation. Case Presentation. This article repor...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2021/4545375 |
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| author | Mequanent Tariku Adow Shimelis Fantu Gebresilasie Natnael Alemayehu Abebe |
| author_facet | Mequanent Tariku Adow Shimelis Fantu Gebresilasie Natnael Alemayehu Abebe |
| author_sort | Mequanent Tariku Adow |
| collection | DOAJ |
| description | Background. Primary pure ovarian choriocarcinoma is a rare aggressive tumor which can be nongestational arising from germ cells or gestational origin. Preoperative diagnosis of extrauterine choriocarcinoma is challenging due to nonspecific clinical presentation. Case Presentation. This article reports primary ovarian choriocarcinoma, likely gestational in a 25-year-old para 2 woman presenting with lower abdominal pain and swelling of two-week duration. Diagnosis was suspected by serum beta-human chorionic gonadotropin and confirmed histologically after surgery. Postoperatively, she was managed with multiple courses of chemotherapy using a bleomycin, etoposide, and cisplatin regimen, and the treatment was effective. Conclusion. In patients with adnexal mass presenting with nonspecific symptoms especially with high Doppler blood flow of the mass on ultrasound evaluation, serum beta-human chorionic gonadotropin determination is recommended before laparotomy. In setups where the genomic test is not available, histological and clinical effort to differentiate gestational versus nongestational choriocarcinoma is useful for specific management decision. |
| format | Article |
| id | doaj-art-f631ab1fee4a48b79df40ff107fc8aaf |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-f631ab1fee4a48b79df40ff107fc8aaf2025-02-03T01:27:24ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922021-01-01202110.1155/2021/45453754545375Primary Ovarian Choriocarcinoma: Rare EntityMequanent Tariku Adow0Shimelis Fantu Gebresilasie1Natnael Alemayehu Abebe2Debre Tabor University, College of Health Science, Debre Tabor, EthiopiaHawassa University, College of Medicine and Health Science, Hawassa, EthiopiaHawassa University, College of Medicine and Health Science, Hawassa, EthiopiaBackground. Primary pure ovarian choriocarcinoma is a rare aggressive tumor which can be nongestational arising from germ cells or gestational origin. Preoperative diagnosis of extrauterine choriocarcinoma is challenging due to nonspecific clinical presentation. Case Presentation. This article reports primary ovarian choriocarcinoma, likely gestational in a 25-year-old para 2 woman presenting with lower abdominal pain and swelling of two-week duration. Diagnosis was suspected by serum beta-human chorionic gonadotropin and confirmed histologically after surgery. Postoperatively, she was managed with multiple courses of chemotherapy using a bleomycin, etoposide, and cisplatin regimen, and the treatment was effective. Conclusion. In patients with adnexal mass presenting with nonspecific symptoms especially with high Doppler blood flow of the mass on ultrasound evaluation, serum beta-human chorionic gonadotropin determination is recommended before laparotomy. In setups where the genomic test is not available, histological and clinical effort to differentiate gestational versus nongestational choriocarcinoma is useful for specific management decision.http://dx.doi.org/10.1155/2021/4545375 |
| spellingShingle | Mequanent Tariku Adow Shimelis Fantu Gebresilasie Natnael Alemayehu Abebe Primary Ovarian Choriocarcinoma: Rare Entity Case Reports in Obstetrics and Gynecology |
| title | Primary Ovarian Choriocarcinoma: Rare Entity |
| title_full | Primary Ovarian Choriocarcinoma: Rare Entity |
| title_fullStr | Primary Ovarian Choriocarcinoma: Rare Entity |
| title_full_unstemmed | Primary Ovarian Choriocarcinoma: Rare Entity |
| title_short | Primary Ovarian Choriocarcinoma: Rare Entity |
| title_sort | primary ovarian choriocarcinoma rare entity |
| url | http://dx.doi.org/10.1155/2021/4545375 |
| work_keys_str_mv | AT mequanenttarikuadow primaryovarianchoriocarcinomarareentity AT shimelisfantugebresilasie primaryovarianchoriocarcinomarareentity AT natnaelalemayehuabebe primaryovarianchoriocarcinomarareentity |