Comprehensive characterization of PD-L1 expression and immunotherapy-related genomic biomarkers in early- versus advanced-stage non-small cell lung cancer

Comprehensive characterization of PD-L1 expression and immunotherapy-related genomic biomarkers in early- versus advanced-stage non-small cell lung cancer

Abstract Background Programmed death-ligand 1 (PD-L1) expression is a key biomarker for predicting the efficacy of immune checkpoint inhibitors (ICIs). With the successful application of perioperative immunotherapy, understanding PD-L1-associated clinical and molecular characteristics in early-stage...

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Bibliographic Details
Main Authors: Yujie Chen, Peiyuan Wang, Rong Lian, Mingming Yuan, Pengli Yu, Hao He, Peng Chen, Hang Zhou, Weijie Chen, Derong Zhang, Hui Lin, Shuoyan Liu, Feng Wang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Pulmonary Medicine
Subjects:
PD-L1
Immunotherapy
LUAD
LUSC
Stage
Online Access:https://doi.org/10.1186/s12890-025-03687-w
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