Immunogenic recombinant Mayaro virus-like particles present natively assembled glycoprotein

Immunogenic recombinant Mayaro virus-like particles present natively assembled glycoprotein

Abstract Virus-like particles (VLPs) are an established vaccine platform and can be strong immunogens capable of eliciting both humoral and cellular immune responses against a range of pathogens. Here, we show by cryo-electron microscopy that VLPs of Mayaro virus, which contain envelope glycoprotein...

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Main Authors: Young Chan Kim, Yasunori Watanabe, Arlen-Celina Lücke, Xiyong Song, Raquel de Oliveira Souza, Robert Stass, Sasha R. Azar, Shannan L. Rossi, Carla Claser, Beate Mareike Kümmerer, Max Crispin, Thomas A. Bowden, Juha T. Huiskonen, Arturo Reyes-Sandoval
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-01021-9
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https://doi.org/10.1038/s41541-024-01021-9

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