Isolated Adrenocorticotropin Deficiency Associated with Delirium and Takotsubo Cardiomyopathy
We report a 65-year-old woman with isolated adrenocorticotropic hormone (ACTH) deficiency. The patient was transported to the emergency outpatient department by ambulance complaining of malaise and nausea. Because her laboratory data revealed hyponatremia, we performed endocrinological examinations...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2012/580481 |
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| _version_ | 1832565208780898304 |
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| author | Masanori Murakami Noriko Matsushita Rie Arai Naohiro Takahashi Ryuki Kawamura Sayaka Suzuki Sachio Takekawa Fumiko Iwashima Takashi Shibui Akihiro Hata Yoshihiro Ogawa Toshiyuki Horiuchi |
| author_facet | Masanori Murakami Noriko Matsushita Rie Arai Naohiro Takahashi Ryuki Kawamura Sayaka Suzuki Sachio Takekawa Fumiko Iwashima Takashi Shibui Akihiro Hata Yoshihiro Ogawa Toshiyuki Horiuchi |
| author_sort | Masanori Murakami |
| collection | DOAJ |
| description | We report a 65-year-old woman with isolated adrenocorticotropic hormone (ACTH) deficiency. The patient was transported to the emergency outpatient department by ambulance complaining of malaise and nausea. Because her laboratory data revealed hyponatremia, we performed endocrinological examinations and diagnosed isolated ACTH deficiency. After admission, she went into a delirious state and suffered from takotsubo cardiomyopathy due to adrenal insufficiency. Replacement therapy with hydrocortisone sufficiently improved her delirium and cardiomyopathy. We conclude that her unstable mental state and myocardial dysfunction were closely related to adrenal insufficiency and suggest that adrenal crisis may cause delirium and Takotsubo cardiomyopathy. |
| format | Article |
| id | doaj-art-f61ba9050a774d6a8767fca64c75a6b2 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-f61ba9050a774d6a8767fca64c75a6b22025-02-03T01:09:09ZengWileyCase Reports in Endocrinology2090-65012090-651X2012-01-01201210.1155/2012/580481580481Isolated Adrenocorticotropin Deficiency Associated with Delirium and Takotsubo CardiomyopathyMasanori Murakami0Noriko Matsushita1Rie Arai2Naohiro Takahashi3Ryuki Kawamura4Sayaka Suzuki5Sachio Takekawa6Fumiko Iwashima7Takashi Shibui8Akihiro Hata9Yoshihiro Ogawa10Toshiyuki Horiuchi11Department of Endocrinology and Metabolism, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital, 33-1 Sakae-cho, Itabashi-ku, Tokyo 173-0015, JapanDepartment of Cardiology, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital, 33-1 Sakae-cho, Itabashi-ku, Tokyo 173-0015, JapanDepartment of Psychiatry, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital, 33-1 Sakae-cho, Itabashi-ku, Tokyo 173-0015, JapanDepartment of Endocrinology and Metabolism, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital, 33-1 Sakae-cho, Itabashi-ku, Tokyo 173-0015, JapanDepartment of Cardiology, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital, 33-1 Sakae-cho, Itabashi-ku, Tokyo 173-0015, JapanDepartment of Endocrinology and Metabolism, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital, 33-1 Sakae-cho, Itabashi-ku, Tokyo 173-0015, JapanDepartment of Endocrinology and Metabolism, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital, 33-1 Sakae-cho, Itabashi-ku, Tokyo 173-0015, JapanDepartment of Endocrinology and Metabolism, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital, 33-1 Sakae-cho, Itabashi-ku, Tokyo 173-0015, JapanDepartment of Cardiology, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital, 33-1 Sakae-cho, Itabashi-ku, Tokyo 173-0015, JapanDepartment of Cardiology, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital, 33-1 Sakae-cho, Itabashi-ku, Tokyo 173-0015, JapanDepartment of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, JapanDepartment of Endocrinology and Metabolism, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital, 33-1 Sakae-cho, Itabashi-ku, Tokyo 173-0015, JapanWe report a 65-year-old woman with isolated adrenocorticotropic hormone (ACTH) deficiency. The patient was transported to the emergency outpatient department by ambulance complaining of malaise and nausea. Because her laboratory data revealed hyponatremia, we performed endocrinological examinations and diagnosed isolated ACTH deficiency. After admission, she went into a delirious state and suffered from takotsubo cardiomyopathy due to adrenal insufficiency. Replacement therapy with hydrocortisone sufficiently improved her delirium and cardiomyopathy. We conclude that her unstable mental state and myocardial dysfunction were closely related to adrenal insufficiency and suggest that adrenal crisis may cause delirium and Takotsubo cardiomyopathy.http://dx.doi.org/10.1155/2012/580481 |
| spellingShingle | Masanori Murakami Noriko Matsushita Rie Arai Naohiro Takahashi Ryuki Kawamura Sayaka Suzuki Sachio Takekawa Fumiko Iwashima Takashi Shibui Akihiro Hata Yoshihiro Ogawa Toshiyuki Horiuchi Isolated Adrenocorticotropin Deficiency Associated with Delirium and Takotsubo Cardiomyopathy Case Reports in Endocrinology |
| title | Isolated Adrenocorticotropin Deficiency Associated with Delirium and Takotsubo Cardiomyopathy |
| title_full | Isolated Adrenocorticotropin Deficiency Associated with Delirium and Takotsubo Cardiomyopathy |
| title_fullStr | Isolated Adrenocorticotropin Deficiency Associated with Delirium and Takotsubo Cardiomyopathy |
| title_full_unstemmed | Isolated Adrenocorticotropin Deficiency Associated with Delirium and Takotsubo Cardiomyopathy |
| title_short | Isolated Adrenocorticotropin Deficiency Associated with Delirium and Takotsubo Cardiomyopathy |
| title_sort | isolated adrenocorticotropin deficiency associated with delirium and takotsubo cardiomyopathy |
| url | http://dx.doi.org/10.1155/2012/580481 |
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