Uncovering Non-Invasive Biomarkers in Paediatric Severe Acute Asthma Using Targeted Exhaled Breath Analysis

Uncovering Non-Invasive Biomarkers in Paediatric Severe Acute Asthma Using Targeted Exhaled Breath Analysis

Background: Severe acute asthma (SAA) in children can be life-threatening. There has been a significant rise in paediatric intensive care unit (PICU) admissions due to SAA over the past two decades. While asthma is a heterogeneous disease, its underlying pathophysiological pathways remain underexplo...

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Main Authors: Sarah van den Berg, Annabel S. Zaat, Isabel F. van der Poel, Yoni E. van Dijk, Simone Hashimoto, Niels W. P. Rutjes, Suzanne W. J. Terheggen-Largo, Bart E. van Ewijk, Claudia Gagliani, Fleur L. Sondaal, Job B. M. van Woensel, Anke-Hilse Maitland-van der Zee, Paul Brinkman, Susanne J. H. Vijverberg, Berber Kapitein
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Metabolites
Subjects:
severe acute asthma
paediatrics
paediatric intensive care unit
breathomics
volatile organic compounds
thermal desorption gas chromatography–mass spectrometry
Online Access:https://www.mdpi.com/2218-1989/15/4/247
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