Itaconate: A Nexus Metabolite Fueling <i>Leishmania</i> Survival Through Lipid Metabolism Modulation

Leishmaniasis, caused by the <i>Leishmania</i> parasite, is a neglected public health issue. <i>Leishmania</i> mainly infects macrophages, where metabolic reprogramming shapes their plasticity (M1/M2), affecting the host’s resistance or susceptibility to infection. The develo...

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Bibliographic Details
Main Authors: Ayyoub Kihel, Hajar El Filaly, Dounia Darif, Aicha Assouab, Myriam Riyad, Imane Nait Irahal, Khadija Akarid
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/13/3/531
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