Modular RNA motifs for orthogonal phase separated compartments

Abstract Recent discoveries in biology have highlighted the importance of protein and RNA-based condensates as an alternative to classical membrane-bound organelles. Here, we demonstrate the design of pure RNA condensates from nanostructured, star-shaped RNA motifs. We generate condensates using two...

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Bibliographic Details
Main Authors: Jaimie Marie Stewart, Shiyi Li, Anli A. Tang, Melissa Ann Klocke, Martin Vincent Gobry, Giacomo Fabrini, Lorenzo Di Michele, Paul W. K. Rothemund, Elisa Franco
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-50003-x
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