High number of CD14+B7H4+ monocytes is significantly associated with increased concentrations of IL-4, IL-13, IL-10, and TGF-β1 in tumor microcirculation of lung carcinoma

High number of CD14+B7H4+ monocytes is significantly associated with increased concentrations of IL-4, IL-13, IL-10, and TGF-β1 in tumor microcirculation of lung carcinoma

Background/Aim. Lung cancer (LC) is one of the leading causes of mortality. Disease progression and advanced disease are characterized by the unprotective immune response due to M2 macrophage polarization, myeloid-derived suppressor cells (MDSC) activity, cytokine imbalance, and regulatory T lymphoc...

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Main Authors: Vuković Jelena, Nikolić Nevena, Karličić Vukoica, Stanojević Ivan, Šupić Gordana, Jović Milena, Štefik Debora, Abazović Dzihan, Vojvodić Danilo
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2021-01-01
Series:Vojnosanitetski Pregled
Subjects:
antigens, cd
blood
cytokines
histological techniques
lung neoplasms
monocytes
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84502000043V.pdf
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http://www.doiserbia.nb.rs/img/doi/0042-8450/2021/0042-84502000043V.pdf

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