Substrate-Induced Structural Dynamics and Evolutionary Linkage of Siderophore-Iron ABC Transporters of <i>Mycobacterium tuberculosis</i>

Substrate-Induced Structural Dynamics and Evolutionary Linkage of Siderophore-Iron ABC Transporters of <i>Mycobacterium tuberculosis</i>

<i>Background and Objective</i>: ATP-binding cassette (ABC) transporters are prominent drug targets due to their highly efficient trafficking capabilities and their significant physiological and clinical roles. Gaining insight into their biophysical and biomechanistic properties is cruci...

Full description

Saved in:
Bibliographic Details
Main Authors: Aisha Farhana, Abdullah Alsrhani, Hasan Ejaz, Muharib Alruwaili, Ayman A. M. Alameen, Emad Manni, Zafar Rasheed, Yusuf Saleem Khan
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Medicina
Subjects:
<i>Mycobacterium tuberculosis</i>
siderophore-iron uptake
ABC transporters
Rv1348 (IrtA) and Rv2895c (IrtB)
evolutionary linkage of transporters
drug targeting
Online Access:https://www.mdpi.com/1648-9144/60/11/1891
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1648-9144/60/11/1891

Similar Items