Adaptive Resistance of <i>Staphylococcus aureus</i> to Cefquinome Sulfate in an In Vitro Pharmacokinetic Model with Transcriptomic Insights

Adaptive Resistance of <i>Staphylococcus aureus</i> to Cefquinome Sulfate in an In Vitro Pharmacokinetic Model with Transcriptomic Insights

Cefquinome sulfate has a strong killing effect against <i>Staphylococcus aureus</i> (<i>S. aureus</i>), but bacterial resistance has become increasingly widespread. Experiments were conducted to investigate the pattern of adaptive resistance of <i>S. aureus</i> to...

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Bibliographic Details
Main Authors: Yue Hu, Hao Zhu, Xingbo Zhang, Yuhui Wu, Jingtao Li, Nan Li, Zhanbo Cai, Yuhui Yang
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Microorganisms
Subjects:
cefquinome sulfate
<i>Staphylococcus aureus</i>
pharmacokinetic model in vitro
adaptive drug resistance
transcriptional sequencing
Online Access:https://www.mdpi.com/2076-2607/13/2/329
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