Injection of human umbilical cord mesenchymal stem cells exosomes for the treatment of knee osteoarthritis: from preclinical to clinical research

Injection of human umbilical cord mesenchymal stem cells exosomes for the treatment of knee osteoarthritis: from preclinical to clinical research

Abstract Background Background: Exosomes (Exos) derived from mesenchymal stem cells (MSCs) share similar biological functions with MSCs but are more stable under various pathophysiological conditions, with a lower risk of immune rejection. Human umbilical cord mesenchymal stem cells (hUC-MSCs) are a...

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Main Authors: Yuzhong Wang, Yajie Kong, Jiejie Du, Lifei Qi, Meiling Liu, Siyi Xie, Jianghui Hao, Ming Li, Shuxing Cao, Huixian Cui, Aijing Liu, Jun Ma, Yongzhou Song
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Translational Medicine
Subjects:
Osteoarthritis
Exosomes
Human umbilical cord mesenchymal stem cells
Clinical research
Online Access:https://doi.org/10.1186/s12967-025-06623-y
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https://doi.org/10.1186/s12967-025-06623-y

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