Diverse modes of ceftazidime/avibactam resistance acquisition in carbapenem-resistant Klebsiella pneumoniae and Pseudomonas aeruginosa from a Chinese intensive care unit

Diverse modes of ceftazidime/avibactam resistance acquisition in carbapenem-resistant Klebsiella pneumoniae and Pseudomonas aeruginosa from a Chinese intensive care unit

Abstract Objectives To investigate the mechanisms of ceftazidime/avibactam (CZA) resistance and the nosocomial dissemination of carbapenem-resistant Pseudomonas aeruginosa (CRPA) and carbapenem-resistant Klebsiella pneumoniae (CRKP) in an intensive care unit (ICU) in China. Methods Clinical CRPA and...

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Bibliographic Details
Main Authors: Junxin Zhou, Minhua Chen, Min Liang, Xinhong Han, Rui Weng, Yue Li, Yan Jiang, Xiaoting Hua, Xiaoxing Du, Weiping Wang, Zhihui Zhou, Yunsong Yu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Pseudomonas aeruginosa
Klebsiella pneumoniae
Ceftazidime/avibactam
KPC
Non-Tn4401 elements
Cross-regional transmission
Online Access:https://doi.org/10.1186/s12941-025-00800-z
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https://doi.org/10.1186/s12941-025-00800-z

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