From signaling pathways to clinical trials: mesenchymal stem cells as multimodal regenerative architects in liver cirrhosis therapy

From signaling pathways to clinical trials: mesenchymal stem cells as multimodal regenerative architects in liver cirrhosis therapy

Abstract Liver cirrhosis, a chronic disease distinguished by extensive scarring in the liver, results in liver dysfunction and fatal complications such as portal hypertension and liver cancer. Although early interventions can retard or reverse early injury, advanced stages often call for liver trans...

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Bibliographic Details
Main Authors: Vida Bozorgi, Mahnaz Babaahmadi, Mohammad Salehi, Jamshid Vafaeimanesh, Ensiyeh Hajizadeh-Saffar
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Liver cirrhosis
MSC-EVs
MSC
Online Access:https://doi.org/10.1186/s13287-025-04535-8
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