Delirium with Concurrent Use of Lithium and ECT and the Safety Implications: Case Reports and Review of the Literature
Using electroconvulsive treatment and lithium together to treat acute manic episodes is common, but the effects of combining these therapies vary according to the literature. Some studies have found severe adverse side effects, while others have found the combination of both medications safe and hel...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2023/9117292 |
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| author | Mustafa Ali Barikar C. Malathesh Seshadri Sekhar Chatterjee Soumitra Das Prakriti Pokhrel Mary Elizabeth Trejo Hernandez John C. Murnin |
| author_facet | Mustafa Ali Barikar C. Malathesh Seshadri Sekhar Chatterjee Soumitra Das Prakriti Pokhrel Mary Elizabeth Trejo Hernandez John C. Murnin |
| author_sort | Mustafa Ali |
| collection | DOAJ |
| description | Using electroconvulsive treatment and lithium together to treat acute manic episodes is common, but the effects of combining these therapies vary according to the literature. Some studies have found severe adverse side effects, while others have found the combination of both medications safe and helpful. To investigate potential adverse side effects, this study reports on two cases where bipolar affective disorder patients developed delirium after receiving electroconvulsive therapy and lithium concurrently. The delirium was attributed only to the combined administration of these medicines after ruling out other potential causes. Additionally, alterations in blood-brain barrier permeability, such as those caused by electroconvulsive therapy and age, increased the likelihood of delirium. As a result, caution should be taken when using this combination of medicines, especially in those predisposed to delirium. This study established links between these medications and adverse effects, such as delirium. Further research is necessary to determine the efficacy and risks of combining these medications, establish causality, and develop prevention strategies. |
| format | Article |
| id | doaj-art-f3fd19f9147f42cf8b274e88e131419d |
| institution | Kabale University |
| issn | 2090-6838 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj-art-f3fd19f9147f42cf8b274e88e131419d2025-02-03T06:42:44ZengWileyCase Reports in Psychiatry2090-68382023-01-01202310.1155/2023/9117292Delirium with Concurrent Use of Lithium and ECT and the Safety Implications: Case Reports and Review of the LiteratureMustafa Ali0Barikar C. Malathesh1Seshadri Sekhar Chatterjee2Soumitra Das3Prakriti Pokhrel4Mary Elizabeth Trejo Hernandez5John C. Murnin6Government Medical CollegeAll India Institute of Medical SciencesQueensland HealthRoyal Melbourne HospitalKathmandu Medical College Teaching HospitalUniversidad Autonoma de Guadalajara School of MedicineBurrell College of Osteopathic MedicineUsing electroconvulsive treatment and lithium together to treat acute manic episodes is common, but the effects of combining these therapies vary according to the literature. Some studies have found severe adverse side effects, while others have found the combination of both medications safe and helpful. To investigate potential adverse side effects, this study reports on two cases where bipolar affective disorder patients developed delirium after receiving electroconvulsive therapy and lithium concurrently. The delirium was attributed only to the combined administration of these medicines after ruling out other potential causes. Additionally, alterations in blood-brain barrier permeability, such as those caused by electroconvulsive therapy and age, increased the likelihood of delirium. As a result, caution should be taken when using this combination of medicines, especially in those predisposed to delirium. This study established links between these medications and adverse effects, such as delirium. Further research is necessary to determine the efficacy and risks of combining these medications, establish causality, and develop prevention strategies.http://dx.doi.org/10.1155/2023/9117292 |
| spellingShingle | Mustafa Ali Barikar C. Malathesh Seshadri Sekhar Chatterjee Soumitra Das Prakriti Pokhrel Mary Elizabeth Trejo Hernandez John C. Murnin Delirium with Concurrent Use of Lithium and ECT and the Safety Implications: Case Reports and Review of the Literature Case Reports in Psychiatry |
| title | Delirium with Concurrent Use of Lithium and ECT and the Safety Implications: Case Reports and Review of the Literature |
| title_full | Delirium with Concurrent Use of Lithium and ECT and the Safety Implications: Case Reports and Review of the Literature |
| title_fullStr | Delirium with Concurrent Use of Lithium and ECT and the Safety Implications: Case Reports and Review of the Literature |
| title_full_unstemmed | Delirium with Concurrent Use of Lithium and ECT and the Safety Implications: Case Reports and Review of the Literature |
| title_short | Delirium with Concurrent Use of Lithium and ECT and the Safety Implications: Case Reports and Review of the Literature |
| title_sort | delirium with concurrent use of lithium and ect and the safety implications case reports and review of the literature |
| url | http://dx.doi.org/10.1155/2023/9117292 |
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