Spatial patterns of hepatocyte glucose flux revealed by stable isotope tracing and multi-scale microscopy

Spatial patterns of hepatocyte glucose flux revealed by stable isotope tracing and multi-scale microscopy

Abstract Metabolic homeostasis requires engagement of catabolic and anabolic pathways consuming nutrients that generate and consume energy and biomass. Our current understanding of cell homeostasis and metabolism, including how cells utilize nutrients, comes largely from tissue and cell models analy...

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Main Authors: Aliyah Habashy, Christopher Acree, Keun-Young Kim, Ali Zahraei, Martin Dufresne, Sebastien Phan, Melanie Cutler, Emilee Patterson, Alexandra G. Mulligan, Kristopher Burkewitz, Charles Robert Flynn, Louise Lantier, Thomas Deerinck, Owen P. McGuinness, Jeffrey M. Spraggins, Mark H. Ellisman, Rafael Arrojo e Drigo
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60994-w
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https://doi.org/10.1038/s41467-025-60994-w

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