Transcriptional regulation of ETV5 by mitogen-activated protein kinase via ETS-1 in human pancreatic cancer cells

Abstract Pancreatic cancer is characterized by constitutive activation of mitogen-activated protein kinase /extracellular signal-regulated kinase 1/2 (ERK1/2) driven by gain-of-function mutations of KRAS. Our previous transcriptome sequencing of ERK1/2-attenuated cultured pancreatic cancer cells unv...

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Bibliographic Details
Main Authors: Aya Noguchi, Masanobu Kimura, Yuriko Saiki, Tomohiko Ishikawa, Takashi Kokumai, Yuko Omori, Yusuke Ono, Yusuke Miszukami, Masaharu Ishida, Masamichi Mizuma, Kei Nakagawa, Michiaki Unno, Toru Furukawa
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-97166-1
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