Mapping dynamic regulation of gene expression using single-cell transcriptomics and application to complex disease genetics

Summary: Single-cell transcriptome data can provide insights into how genetic variation influences biological processes involved in human physiology and disease. However, the identification of gene-level associations in distinct cell types faces several challenges, including the limited reference re...

Full description

Saved in:
Bibliographic Details
Main Authors: Hanna Abe, Phillip Lin, Dan Zhou, Douglas M. Ruderfer, Eric R. Gamazon
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:HGG Advances
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247724001374
Tags: Add Tag
No Tags, Be the first to tag this record!