Hippocampal CA1 Pyramidal Neurons of Mecp2 Mutant Mice Show a Dendritic Spine Phenotype Only in the Presymptomatic Stage
Alterations in dendritic spines have been documented in numerous neurodevelopmental disorders, including Rett Syndrome (RTT). RTT, an X chromosome-linked disorder associated with mutations in MECP2, is the leading cause of intellectual disabilities in women. Neurons in Mecp...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2012/976164 |
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