Involvement of dysregulated RNA binding protein and alternative splicing regulatory networks in diabetic nephropathy from type 2 albuminuric cohorts

Involvement of dysregulated RNA binding protein and alternative splicing regulatory networks in diabetic nephropathy from type 2 albuminuric cohorts

Abstract Background Diabetic nephropathy (DN) is a primary contributor to end-stage renal disease, yet the underlying molecular mechanisms remain incompletely understood. This study aims to elucidate the role of RNA-binding proteins (RBPs) and RBP-alternative splicing (AS) regulatory networks in the...

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Bibliographic Details
Main Authors: Yu Wang, Jingjing Zhang, Qian Tang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Nephrology
Subjects:
Diabetic nephropathy
Transcriptome
Alternative splicing
RNA binding protein
Co-expression
Online Access:https://doi.org/10.1186/s12882-025-04237-6
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https://doi.org/10.1186/s12882-025-04237-6

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