X-linked lymphoproliferative disease type 1: a clinical and genetic update

X-linked lymphoproliferative disease (XLP), also known as Duncan’s disease, is a primary immunodeficiency disorder linked to the X chromosome. In 1998, SH2D1A, which encodes the signaling lymphocyte activation molecule (SLAM)-associated protein (SAP), was identified as the first pathogenic gene asso...

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Main Authors: Jiaxun Li, Luyu Lv, Qingqing Wei, Wenpeng Pang, Chunjuan He, Hao Wu, Liping Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1620327/full
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