Enhanced Biofilm Disruption in Methicillin-Resistant <i>Staphylococcus aureus</i> Using Rifampin and Fluoroquinolone Combinations

Enhanced Biofilm Disruption in Methicillin-Resistant <i>Staphylococcus aureus</i> Using Rifampin and Fluoroquinolone Combinations

<i>Staphylococcus aureus</i> biofilms complicate the treatment of device-related infections. We hypothesized that combining rifampin with fluoroquinolones could eradicate biofilms even in antimicrobial-resistant <i>S. aureus</i> strains. We determined the synergistic interact...

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Bibliographic Details
Main Authors: Yu Ri Kang, Joo-Young Park, Doo Ryeon Chung, Minhee Kang, Jae-Hoon Ko, Kyungmin Huh, Sun Young Cho, Cheol-In Kang, Kyong Ran Peck
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pathogens
Subjects:
fluoroquinolones
methicillin resistance
microbial viability
drug synergy
confocal microscopy
Online Access:https://www.mdpi.com/2076-0817/14/5/404
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