TLR4 Inhibition Attenuated LPS‐Induced Proinflammatory Signaling and Cytokine Release in Mouse Hearts and Cardiomyocytes
ABSTRACT Background Sepsis is associated with myocardial injury and early mortality. The innate immune receptor Toll‐like receptor 4 (TLR4) can recognize pathogen‐associated‐molecular‐patterns (PAMPs) and damage‐associated molecular patterns (DAMPs); the latter are released during tissue injury. We...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2025-01-01
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Series: | Immunity, Inflammation and Disease |
Subjects: | |
Online Access: | https://doi.org/10.1002/iid3.70133 |
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