Integrative multi-omics investigation of sleep apnea: gut microbiome metabolomics, proteomics and phenome-wide association study

Abstract Background Sleep apnea (SA) is linked to various diseases. This study examines the causal link between the gut microbiome and SA, exploring potential predictive factors and target proteins using a multi-omics approach with a Phenome-wide association study (PheWAS). Methods Bidirectional Men...

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Bibliographic Details
Main Authors: Shuxu Wei, Ronghuai Shen, Xiaojia Lu, Xinyi Li, Lingbin He, Youti Zhang, Xianxi Huang, Zhouwu Shu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Nutrition & Metabolism
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Online Access:https://doi.org/10.1186/s12986-025-00925-0
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