Borrelia burgdorferi radiosensitivity and Mn antioxidant content: antigenic preservation and pathobiology

Borrelia burgdorferi radiosensitivity and Mn antioxidant content: antigenic preservation and pathobiology

ABSTRACT The bacterium responsible for Lyme disease, Borrelia burgdorferi, accumulates high levels of manganese without iron and possesses a polyploid genome, characteristics suggesting potential extreme resistance to radiation. Contrary to expectations, we report that wild-type B. burgdorferi B31 c...

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Main Authors: Andrés F. Londoño, Ajay Sharma, Jared Sealy, Vipin S. Rana, Shelby D. Foor, Vera Y. Matrosova, Elena K. Gaidamakova, Robert P. Volpe, Michael J. Daly, Brian M. Hoffman, Utpal Pal, J. Stephen Dumler
Format: Article
Language:English
Published: American Society for Microbiology 2025-02-01
Series:mBio
Subjects:
Lyme disease
Borrelia
Deinococcus
irradiated vaccine
gamma-radiation
MDP
Online Access:https://journals.asm.org/doi/10.1128/mbio.03131-24
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