ATRX, OLIG2, MGMT, and IDH2 in Glioblastoma: Essential Molecular Mechanisms and Therapeutic Significance

ATRX, OLIG2, MGMT, and IDH2 in Glioblastoma: Essential Molecular Mechanisms and Therapeutic Significance

<i>Background and Objectives</i>: Glioblastoma (GBM) is among the most aggressive and lethal primary brain tumors, characterized by high heterogeneity, invasive growth, and resistance to conventional therapies. The 2021 WHO classification highlights the importance of molecular diagnostic...

Full description

Saved in:
Bibliographic Details
Main Authors: Andrea Pop-Crisan, Radu Pirlog, Lavinia-Lorena Pruteanu, Constantin Busuioc, Ovidiu-Laurean Pop, Deo Prakash Pandey, Cornelia Braicu, Ioana Berindan-Neagoe
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Medicina
Subjects:
glioblastoma
molecular alteration
therapeutic strategy
Online Access:https://www.mdpi.com/1648-9144/61/4/697
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1648-9144/61/4/697

Similar Items