Modelling the evolutionary dynamics of drug resistance in tuberculosis using hypercube and Baum-Welch algorithm inference: A case study of Tanzania

Modelling the evolutionary dynamics of drug resistance in tuberculosis using hypercube and Baum-Welch algorithm inference: A case study of Tanzania

Drug resistance, particularly multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant forms of tuberculosis (XDR-TB), amplifies the global health problem of tuberculosis (TB). To address some of these issues, the study investigated the evolutionary dynamics of drug resistance using...

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Bibliographic Details
Main Authors: Leonce Leandry, Egbert Mujuni, Morten Brun, Eunice W. Mureithi, Mbazi Senkoro, Saidi Mfaume
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Heliyon
Subjects:
Hypercubes
Baum-Welch algorithm
Hidden Markov Model (HMM)
Tuberculosis
Antimicrobial resistance
Tanzania
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025011624
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