Monte Carlo simulation of a novel medical linac concept for highly conformal x-ray FLASH cancer radiotherapy

Monte Carlo simulation of a novel medical linac concept for highly conformal x-ray FLASH cancer radiotherapy

Abstract A growing body of pre-clinical research has demonstrated the potential of ultra-high dose-rate (UHDR) radiotherapy to reduce normal tissue toxicity while maintaining tumor control. However, owing to a wide range of technical difficulties, no existing x-ray systems are capable of highly conf...

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Bibliographic Details
Main Authors: Deae-eddine Krim, Brendan Whelan, Mindy Harkness, Karl Otto, Billy W Loo, Magdalena Bazalova-Carter
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
X-ray UHDR machine
Monte Carlo
Treatment planning system
Optimization
Online Access:https://doi.org/10.1038/s41598-025-02150-4
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