Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus.

Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus.

Several components of the mosquito immune system including the RNA interference (RNAi), JAK/STAT, Toll and IMD pathways have previously been implicated in controlling arbovirus infections. In contrast, the role of the phenoloxidase (PO) cascade in mosquito antiviral immunity is unknown. Here we show...

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Main Authors: Julio Rodriguez-Andres, Seema Rani, Margus Varjak, Margo E Chase-Topping, Markus H Beck, Mhairi C Ferguson, Esther Schnettler, Rennos Fragkoudis, Gerald Barry, Andres Merits, John K Fazakerley, Michael R Strand, Alain Kohl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002977&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002977&type=printable

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