DEVELOPMENT OF NEW HIGHLY ACTIVE L-ALANINE PRODUCER STRAINS OF BREVIBACTERIUM FLAVUM AND COMPARATIVE CHARACTERIZATION OF THEIR ALANINE-SYNTHESIZING ACTIVITY
New mutants, not described previously, resistant to L-cycloserine and β-chloro-L-alanine were derived from the parental strain Brevibacterium flavum AA5. Their alanine-producing ability was studied. It was found that the resistance to L-cycloserine did not affect the yield of L-alanine significantly...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
2015-01-01
|
| Series: | Вавиловский журнал генетики и селекции |
| Subjects: | |
| Online Access: | https://vavilov.elpub.ru/jour/article/view/165 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832575339478384640 |
|---|---|
| author | G. Ye. Avetisova L. H. Melkonyan A. Kh. Chakhalyan S. Gh. Keleshyan A. S. Saghyan |
| author_facet | G. Ye. Avetisova L. H. Melkonyan A. Kh. Chakhalyan S. Gh. Keleshyan A. S. Saghyan |
| author_sort | G. Ye. Avetisova |
| collection | DOAJ |
| description | New mutants, not described previously, resistant to L-cycloserine and β-chloro-L-alanine were derived from the parental strain Brevibacterium flavum AA5. Their alanine-producing ability was studied. It was found that the resistance to L-cycloserine did not affect the yield of L-alanine significantly, whereas the resistance to β-chloro-L-alanine of B. flavum GL1 and B. flavum GL18 strain-producers exceeds the initial level of L-alanine synthesis by 23 and 38 %, respectively. |
| format | Article |
| id | doaj-art-f264887d34c247d7a3b687c4fef098f1 |
| institution | Kabale University |
| issn | 2500-3259 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders |
| record_format | Article |
| series | Вавиловский журнал генетики и селекции |
| spelling | doaj-art-f264887d34c247d7a3b687c4fef098f12025-02-01T09:57:59ZengSiberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and BreedersВавиловский журнал генетики и селекции2500-32592015-01-01173430434149DEVELOPMENT OF NEW HIGHLY ACTIVE L-ALANINE PRODUCER STRAINS OF BREVIBACTERIUM FLAVUM AND COMPARATIVE CHARACTERIZATION OF THEIR ALANINE-SYNTHESIZING ACTIVITYG. Ye. Avetisova0L. H. Melkonyan1A. Kh. Chakhalyan2S. Gh. Keleshyan3A. S. Saghyan4Scientific and Production Center «Armbiotechnology», National Academy of Sciences of Armenia, Yerevan, ArmeniaScientific and Production Center «Armbiotechnology», National Academy of Sciences of Armenia, Yerevan, ArmeniaScientific and Production Center «Armbiotechnology», National Academy of Sciences of Armenia, Yerevan, ArmeniaScientific and Production Center «Armbiotechnology», National Academy of Sciences of Armenia, Yerevan, ArmeniaScientific and Production Center «Armbiotechnology», National Academy of Sciences of Armenia, Yerevan, ArmeniaNew mutants, not described previously, resistant to L-cycloserine and β-chloro-L-alanine were derived from the parental strain Brevibacterium flavum AA5. Their alanine-producing ability was studied. It was found that the resistance to L-cycloserine did not affect the yield of L-alanine significantly, whereas the resistance to β-chloro-L-alanine of B. flavum GL1 and B. flavum GL18 strain-producers exceeds the initial level of L-alanine synthesis by 23 and 38 %, respectively.https://vavilov.elpub.ru/jour/article/view/165brevibacterium flavummutagenesisproducer strainl-alanine |
| spellingShingle | G. Ye. Avetisova L. H. Melkonyan A. Kh. Chakhalyan S. Gh. Keleshyan A. S. Saghyan DEVELOPMENT OF NEW HIGHLY ACTIVE L-ALANINE PRODUCER STRAINS OF BREVIBACTERIUM FLAVUM AND COMPARATIVE CHARACTERIZATION OF THEIR ALANINE-SYNTHESIZING ACTIVITY Вавиловский журнал генетики и селекции brevibacterium flavum mutagenesis producer strain l-alanine |
| title | DEVELOPMENT OF NEW HIGHLY ACTIVE L-ALANINE PRODUCER STRAINS OF BREVIBACTERIUM FLAVUM AND COMPARATIVE CHARACTERIZATION OF THEIR ALANINE-SYNTHESIZING ACTIVITY |
| title_full | DEVELOPMENT OF NEW HIGHLY ACTIVE L-ALANINE PRODUCER STRAINS OF BREVIBACTERIUM FLAVUM AND COMPARATIVE CHARACTERIZATION OF THEIR ALANINE-SYNTHESIZING ACTIVITY |
| title_fullStr | DEVELOPMENT OF NEW HIGHLY ACTIVE L-ALANINE PRODUCER STRAINS OF BREVIBACTERIUM FLAVUM AND COMPARATIVE CHARACTERIZATION OF THEIR ALANINE-SYNTHESIZING ACTIVITY |
| title_full_unstemmed | DEVELOPMENT OF NEW HIGHLY ACTIVE L-ALANINE PRODUCER STRAINS OF BREVIBACTERIUM FLAVUM AND COMPARATIVE CHARACTERIZATION OF THEIR ALANINE-SYNTHESIZING ACTIVITY |
| title_short | DEVELOPMENT OF NEW HIGHLY ACTIVE L-ALANINE PRODUCER STRAINS OF BREVIBACTERIUM FLAVUM AND COMPARATIVE CHARACTERIZATION OF THEIR ALANINE-SYNTHESIZING ACTIVITY |
| title_sort | development of new highly active l alanine producer strains of brevibacterium flavum and comparative characterization of their alanine synthesizing activity |
| topic | brevibacterium flavum mutagenesis producer strain l-alanine |
| url | https://vavilov.elpub.ru/jour/article/view/165 |
| work_keys_str_mv | AT gyeavetisova developmentofnewhighlyactivelalanineproducerstrainsofbrevibacteriumflavumandcomparativecharacterizationoftheiralaninesynthesizingactivity AT lhmelkonyan developmentofnewhighlyactivelalanineproducerstrainsofbrevibacteriumflavumandcomparativecharacterizationoftheiralaninesynthesizingactivity AT akhchakhalyan developmentofnewhighlyactivelalanineproducerstrainsofbrevibacteriumflavumandcomparativecharacterizationoftheiralaninesynthesizingactivity AT sghkeleshyan developmentofnewhighlyactivelalanineproducerstrainsofbrevibacteriumflavumandcomparativecharacterizationoftheiralaninesynthesizingactivity AT assaghyan developmentofnewhighlyactivelalanineproducerstrainsofbrevibacteriumflavumandcomparativecharacterizationoftheiralaninesynthesizingactivity |