MRI Texture Analysis in Multiple Sclerosis

Multiple sclerosis (MS) is a complicated disease characterized by heterogeneous pathology that varies across individuals. Accurate identification and quantification of pathological changes may facilitate a better understanding of disease pathogenesis and progression and help identify novel therapies...

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Main Author: Yunyan Zhang
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2012/762804
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author Yunyan Zhang
author_facet Yunyan Zhang
author_sort Yunyan Zhang
collection DOAJ
description Multiple sclerosis (MS) is a complicated disease characterized by heterogeneous pathology that varies across individuals. Accurate identification and quantification of pathological changes may facilitate a better understanding of disease pathogenesis and progression and help identify novel therapies for MS patients. Texture analysis evaluates interpixel relationships that generate characteristic organizational patterns in an image, many of which are beyond the ability of visual perception. Given its promise detecting subtle structural alterations texture analysis may be an attractive means to evaluate disease activity and evolution. It may also become a new tool to assess therapeutic efficacy if technique issues are resolved and pathological correlates are further confirmed. This paper describes the concept, strategies, and considerations of MRI texture analysis; summarizes applications of texture analysis in MS as a measure of tissue integrity and its clinical relevance; then discusses potentially future directions of texture analysis in MS.
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institution Kabale University
issn 1687-4188
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language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series International Journal of Biomedical Imaging
spelling doaj-art-f1b0dd0dbb1f4389a2950c7a5be914712025-02-03T05:52:40ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962012-01-01201210.1155/2012/762804762804MRI Texture Analysis in Multiple SclerosisYunyan Zhang0Department of Radiology, University of Calgary, Calgary, AB, T2N 1N4, CanadaMultiple sclerosis (MS) is a complicated disease characterized by heterogeneous pathology that varies across individuals. Accurate identification and quantification of pathological changes may facilitate a better understanding of disease pathogenesis and progression and help identify novel therapies for MS patients. Texture analysis evaluates interpixel relationships that generate characteristic organizational patterns in an image, many of which are beyond the ability of visual perception. Given its promise detecting subtle structural alterations texture analysis may be an attractive means to evaluate disease activity and evolution. It may also become a new tool to assess therapeutic efficacy if technique issues are resolved and pathological correlates are further confirmed. This paper describes the concept, strategies, and considerations of MRI texture analysis; summarizes applications of texture analysis in MS as a measure of tissue integrity and its clinical relevance; then discusses potentially future directions of texture analysis in MS.http://dx.doi.org/10.1155/2012/762804
spellingShingle Yunyan Zhang
MRI Texture Analysis in Multiple Sclerosis
International Journal of Biomedical Imaging
title MRI Texture Analysis in Multiple Sclerosis
title_full MRI Texture Analysis in Multiple Sclerosis
title_fullStr MRI Texture Analysis in Multiple Sclerosis
title_full_unstemmed MRI Texture Analysis in Multiple Sclerosis
title_short MRI Texture Analysis in Multiple Sclerosis
title_sort mri texture analysis in multiple sclerosis
url http://dx.doi.org/10.1155/2012/762804
work_keys_str_mv AT yunyanzhang mritextureanalysisinmultiplesclerosis