THE ANALYSIS OF THE RESULTS OF ACUTE LYMPHOBLAST LEUKEMIA TREATMENT IN CHILDREN USING A MODIFIED PROTOCOL COALL 92 IN ST. PETERSBURG
The article presents the results of the treatment of children with acute lymphoblast leukemia (all) according to the coall 92 program in St.-Petersburg from 01.01.1999 to 01.01.2005. 160 primary all patients, aged 4 months to 17 years 4 months were included in the study. International criteria were...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Union of pediatricians of Russia
2006-06-01
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| Series: | Педиатрическая фармакология |
| Online Access: | https://www.pedpharma.ru/jour/article/view/560 |
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| Summary: | The article presents the results of the treatment of children with acute lymphoblast leukemia (all) according to the coall 92 program in St.-Petersburg from 01.01.1999 to 01.01.2005. 160 primary all patients, aged 4 months to 17 years 4 months were included in the study. International criteria were used to diagnose acute lymphoblast leukemia. A 2 years course of treatment in both risk groups included a 5,5–8 months phase of intensive chemotherapy followed by maintenance therapy. 6 years after the protocol introduction in the common group of patients the following survival rate indices were obtained: the 6 years uneventful survival rate was 63 ± 4,6%, the 6 years relapses free survival rate was 69 ± 4,7%, the 6 years general survival rate was 79 ± 3,7%.Key words: acute lymphoblast leukemia, children, intensive chemotherapy. |
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| ISSN: | 1727-5776 2500-3089 |