Generation and characterization of a tamoxifen-inducible lineage tracing tool Cd2-P2A-CreERT2 knock-in mice

IntroductionThe new targeted gene editing technologies, such as the CRISPR/Cas system, enable researchers to insert or delete genes at targeted loci efficiently. The Cre-loxp recombination system is widely used to activate or inactivate genes with high spatial and temporal specificity.MethodsUsing t...

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Bibliographic Details
Main Authors: Yang Guo, Mengyan Zhu, Zhilan Yu, Qing Li, Yanjuan Chen, Lei Ci, Ruilin Sun, Ruling Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1482070/full
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