Exogenous Janus Kinase 617 Codon Influences Small Noncoding RNAs and Gene Expression in Ba/F3 Cells

Exogenous Janus Kinase 617 Codon Influences Small Noncoding RNAs and Gene Expression in Ba/F3 Cells

Myeloproliferative neoplasms (MPNs) are blood cancers caused by mutations that originate from hematopoietic stem cells. More than 50%–90% of MPN patients had a dominant negative valine (V) to phenylalanine (F) mutation at the Janus kinase 617 codon (JAK2V617F) within the Janus kinase (JAK)-signal tr...

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Bibliographic Details
Main Authors: Yi-Yang Chen, Ying-Hsuan Wang, Chih-Cheng Chen, Cih-En Huang, Chia-Chen Hsu, Shu-Huei Hsiao, Yu-Wei Leu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Physiological Investigation
Subjects:
epigenetics
microrna
myeloproliferative neoplasms
piwi-interacting rna
v617f mutation
Online Access:https://journals.lww.com/cjop/fulltext/2024/67060/exogenous_janus_kinase_617_codon_influences_small.6.aspx
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https://journals.lww.com/cjop/fulltext/2024/67060/exogenous_janus_kinase_617_codon_influences_small.6.aspx

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