Lowering Caveolin-1 Expression in Human Vascular Endothelial Cells Inhibits Signal Transduction in Response to Shear Stress
Vascular endothelial cells have an extensive response to physiological levels of shear stress. There is evidence that the protein caveolin-1 is involved in the early phase of this response. In this study, caveolin-1 was downregulated in human endothelial cells by RNAi. When these cells were subjecte...
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Main Authors: | A. D. van der Meer, M. M. J. Kamphuis, A. A. Poot, J. Feijen, I. Vermes |
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Format: | Article |
Language: | English |
Published: |
Wiley
2009-01-01
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Series: | International Journal of Cell Biology |
Online Access: | http://dx.doi.org/10.1155/2009/532432 |
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