Lowering Caveolin-1 Expression in Human Vascular Endothelial Cells Inhibits Signal Transduction in Response to Shear Stress

Vascular endothelial cells have an extensive response to physiological levels of shear stress. There is evidence that the protein caveolin-1 is involved in the early phase of this response. In this study, caveolin-1 was downregulated in human endothelial cells by RNAi. When these cells were subjecte...

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Bibliographic Details
Main Authors: A. D. van der Meer, M. M. J. Kamphuis, A. A. Poot, J. Feijen, I. Vermes
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2009/532432
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