Radiation-induced impacts on mitochondrial DNA and the transgenerational genomic instability

Background: Mitochondrial genomes are dynamically evolving and are shaped by somatic mutation and selection throughout the female germline. In this study, we investigated the radiation-induced impacts on mitochondrial DNA in vitro and in vivo, as well as the transgenerational inheritance. Methods: H...

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Bibliographic Details
Main Authors: Ryosuke Seino, Haruka Kubo, Kai Nishikubo, Hisanori Fukunaga
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Environment International
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Online Access:http://www.sciencedirect.com/science/article/pii/S0160412025000662
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