The level of I-FABP and IgA/IgG to beta-lactoglobulin in mothers at risk for gestational diabetes and in their children: association with antibodies to Bifidobacterium adolescentis and Bifidobacterium breve

The level of I-FABP and IgA/IgG to beta-lactoglobulin in mothers at risk for gestational diabetes and in their children: association with antibodies to Bifidobacterium adolescentis and Bifidobacterium breve

BackgroundThe mechanisms underlying gestational diabetes mellitus (GDM) and their impact on maternal and child immunity remain unclear. We hypothesize that gut microbiome alterations and increased small intestinal permeability contribute to GDM. Intestinal fatty acid-binding protein (I-FABP) leakage...

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Main Authors: Tamara Vorobjova, Aili Tagoma, Celeste Peterson, Ija Talja, Anu Bärenson, Kristi Alnek, Helis Janson, Kaja Metsküla, Anne Kirss, Epp Sepp, Tiiu Rööp, Siiri Kõljalg, Raivo Uibo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
gestational diabetes mellitus
I-FABP
IgA and IgG to beta-lactoglobulin
IgA and IgG to Bifidobacterium
ELISA
immunoblot
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1613002/full
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