Association of Serum 25-Hydroxyl Vitamin D Deficiency and Age-Related Cataract: A Case-Control Study
Purpose. To study the relation between the serum 25-hydroxyl vitamin D (OH D) level and the occurrence of age-related cataract in a case-control study. Patients and Methods. 325 cataract patients and 385 control individuals of both sexes were examined for the 25-OH D level using the chemiluminescent...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2019/9312929 |
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| _version_ | 1832562917534334976 |
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| author | Marwa Mahmoud Abdellah Engy Mohamed Mostafa Eman Hassan Salama Eman Roshdy Mohamed |
| author_facet | Marwa Mahmoud Abdellah Engy Mohamed Mostafa Eman Hassan Salama Eman Roshdy Mohamed |
| author_sort | Marwa Mahmoud Abdellah |
| collection | DOAJ |
| description | Purpose. To study the relation between the serum 25-hydroxyl vitamin D (OH D) level and the occurrence of age-related cataract in a case-control study. Patients and Methods. 325 cataract patients and 385 control individuals of both sexes were examined for the 25-OH D level using the chemiluminescent microparticle immunoassay (CMIA) technology. Results. Mean 25-OH D level in cataract patients was 7.6 ± 5.5 ± 11.2 ng/mL and median was 5.6 (2.6–31.9), while in the control group, mean 25-OH D level was 18.5 ± 9.6 ng/mL and median was 17.8 (3.4–37.8) (p value < 0.001). There was a statistically significant difference among the different types of cataracts with the lowest level in nuclear cataract. Conclusion. 25-OH D levels in all enrolled individuals were below the reference levels with a severe deficiency in cataract patients. These results might highlight the role of deficiency of 25-OH D in age-related cataract patients. |
| format | Article |
| id | doaj-art-f1248ec97dbe4ebf8caa646d06b0b375 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-f1248ec97dbe4ebf8caa646d06b0b3752025-02-03T01:21:35ZengWileyJournal of Ophthalmology2090-004X2090-00582019-01-01201910.1155/2019/93129299312929Association of Serum 25-Hydroxyl Vitamin D Deficiency and Age-Related Cataract: A Case-Control StudyMarwa Mahmoud Abdellah0Engy Mohamed Mostafa1Eman Hassan Salama2Eman Roshdy Mohamed3Ophthalmology Department, Sohag University, Sohag, EgyptOphthalmology Department, Sohag University, Sohag, EgyptClinical Pathology Department, Sohag University, Sohag, EgyptPublic Health Department, Sohag University, Sohag, EgyptPurpose. To study the relation between the serum 25-hydroxyl vitamin D (OH D) level and the occurrence of age-related cataract in a case-control study. Patients and Methods. 325 cataract patients and 385 control individuals of both sexes were examined for the 25-OH D level using the chemiluminescent microparticle immunoassay (CMIA) technology. Results. Mean 25-OH D level in cataract patients was 7.6 ± 5.5 ± 11.2 ng/mL and median was 5.6 (2.6–31.9), while in the control group, mean 25-OH D level was 18.5 ± 9.6 ng/mL and median was 17.8 (3.4–37.8) (p value < 0.001). There was a statistically significant difference among the different types of cataracts with the lowest level in nuclear cataract. Conclusion. 25-OH D levels in all enrolled individuals were below the reference levels with a severe deficiency in cataract patients. These results might highlight the role of deficiency of 25-OH D in age-related cataract patients.http://dx.doi.org/10.1155/2019/9312929 |
| spellingShingle | Marwa Mahmoud Abdellah Engy Mohamed Mostafa Eman Hassan Salama Eman Roshdy Mohamed Association of Serum 25-Hydroxyl Vitamin D Deficiency and Age-Related Cataract: A Case-Control Study Journal of Ophthalmology |
| title | Association of Serum 25-Hydroxyl Vitamin D Deficiency and Age-Related Cataract: A Case-Control Study |
| title_full | Association of Serum 25-Hydroxyl Vitamin D Deficiency and Age-Related Cataract: A Case-Control Study |
| title_fullStr | Association of Serum 25-Hydroxyl Vitamin D Deficiency and Age-Related Cataract: A Case-Control Study |
| title_full_unstemmed | Association of Serum 25-Hydroxyl Vitamin D Deficiency and Age-Related Cataract: A Case-Control Study |
| title_short | Association of Serum 25-Hydroxyl Vitamin D Deficiency and Age-Related Cataract: A Case-Control Study |
| title_sort | association of serum 25 hydroxyl vitamin d deficiency and age related cataract a case control study |
| url | http://dx.doi.org/10.1155/2019/9312929 |
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