Promising horizons in achondroplasia along with the development of new drugs

Achondroplasia (ACH) is a representative skeletal disorder characterized by rhizomelic shortened limbs and short stature. ACH is classified as belonging to the fibroblast growth factor receptor 3 (FGFR3) group. The downstream signal transduction of FGFR3 consists of STAT1 and RAS/RAF/MEK/ERK pathway...

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Bibliographic Details
Main Authors: Keiichi Ozono, Takuo Kubota, Toshimi Michigami
Format: Article
Language:English
Published: The Japan Endocrine Society 2024-07-01
Series:Endocrine Journal
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Online Access:https://www.jstage.jst.go.jp/article/endocrj/71/7/71_EJ24-0109/_html/-char/en
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