Proteolytic Processing of CD44 and Its Implications in Cancer

CD44 is a transmembrane glycoprotein expressed in several healthy and tumor tissues. Modifications in its structure contribute differently to the activity of this molecule. One modification that has provoked interest is the consecutive cleavage of the CD44 extracellular ectodomain by enzymes that be...

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Bibliographic Details
Main Authors: Priscila Anhel Medrano-González, Osmar Rivera-Ramírez, Luis Felipe Montaño, Erika P. Rendón-Huerta
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2021/6667735
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